ROS Are Required for Mouse Spermatogonial Stem Cell Self-Renewal
نویسندگان
چکیده
منابع مشابه
ROS are required for mouse spermatogonial stem cell self-renewal.
Reactive oxygen species (ROS) generation is implicated in stem cell self-renewal in several tissues but is thought to be detrimental for spermatogenesis as well as spermatogonial stem cells (SSCs). Using cultured SSCs, we show that ROS are generated via the AKT and MEK signaling pathways under conditions where the growth factors glial cell line-derived neurotrophic factor and fibroblast growth ...
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ژورنال
عنوان ژورنال: Cell Stem Cell
سال: 2013
ISSN: 1934-5909
DOI: 10.1016/j.stem.2013.04.001